Celebrex Medication - Uses & Side Effects
Brand name: Celebrex
Pronounced: SELL-eh-breks
Generic name: Celecoxib
Celebrex is prescribed for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis. The inactive ingredients in Celebrex capsules include: croscarmellose sodium, edible inks, gelatin, lactose monohydrate, magnesium stearate, povidone, sodium lauryl sulfate and titanium dioxide. Celebrex has not been shown to reduce colorectal, duodenal or other FAP-related cancers. Celebrex works by preventing the formation of "inflammatory" prostaglandins. Celecoxib is in a class of NSAIDs called COX-2 inhibitors. It works by stopping the body's production of a substance that causes pain and inflammation. Recent information suggests a possible increased risk for heart attack and stroke in patients taking Celebrex. Celebrex, the brand name of the generic drug celecoxib, was approved by the U.S. Food and Drug Administration (FDA) on December 31, 1998, for the treatment of rheumatoid arthritis. It is marketed by Pfizer under the brand name Celebrex .
Celebrex Dosage:
- Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals.
- For the management of osteoarthritis, the dose usually is 100 mg twice daily or 200 mg as a single dose.
- For relief of the signs and symptoms of rheumatoid arthritis the recommended oral dose is 100 to 200 mg twice per day.
- For FAP, the recommended dose is 400 mg twice daily.
Uses of Celebrex:
- Celebrex is prescribed for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis.
- Celecoxib is also used to treat painful menstrual periods and pain from other causes.
- It is also used with surgery and other treatments to reduce the number of polyps (abnormal growths) in the colon.
- It works by stopping the body's production of a substance that causes pain and inflammation.
- This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Side Effects of Celebrex:
Some common side effects reported with this medicine include:
- Abdominal pain.
- Sinus inflammation.
- Blood disorders.
- Diarrhea.
- Weakness.
- Dark-tarry stools.
- Difficulty breathing.
- Gas or bloating.
- Cold symptoms.
- Stomach and intestinal ulcers.
- Photosensitivity.
- Water retention.
- Drowsiness.
- Dry mouth.
- Esophageal perforation.
- Allergic reactions can occur with celecoxib.
Warnings and precautions before taking Celebrex:
- Patients should be informed about the signs and/or symptoms of serious CV toxicity and the steps to take if they occur.
- Remember to tell your doctor about any stomach ulcers or bleeding you've had in the past.
- Chronic use of Celebrex may cause an increased risk of serious adverse cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal.
- Do not take any more celecoxib until you speak to your doctor.
- Serious problems from stomach ulcers such as bleeding are recognized complications in people treated with NSAID's.
- Do not take Celebrex if you have had an allergic-type reaction to sulfa medicines.
- Tell your doctor if you are pregnant, especially during your last 3 months.
Drug Interaction:
- Concomitant use of celecoxib with aspirin or other NSAIDs (e.g., ibuprofen , naproxen , etc.) may increase the occurrence of stomach and intestinal ulcers.
- Drugs other than those listed here may also interact with Celebrex.
- Celecoxib increases the concentration of lithium (Eskalith) in the blood by 17%.
- Fluconazole (Diflucan) increases the concentration of celecoxib in the body by inhibiting the breakdown of celecoxib in the liver.
Overdosage:
- After taking Celebrex, If you feel that overdose is suspected, then contact with your doctor immediately.
- Symptoms of a Celebrex overdose include drowsiness, nausea, stomach pain, dizziness, headache, little or no urine production, and coma.
- In case of overdose, call your local poison control center at 1-800-222-1222.
- If the victim has collapsed or is not breathing, call local emergency services at 911.
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