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Diabinese Medication - Uses & Side Effects



Pronounced: dye-AB-in-eez

Brand name: Diabinese

Generic name: Chlorpropamide

Diabinese is an oral antidiabetic medication used to treat type 2 (non-insulin-dependent) diabetes. It is indicated as an adjunct to diet to lower the blood glucose in patients with non-insulin-dependent diabetes mellitus (type II) whose hyperglycemia cannot be controlled by diet alone. Diabetes occurs when the body fails to produce enough insulin or is unable to use it properly. Insulin is believed to work by helping sugar penetrate the cell wall so it can be used by the cell. Many people with type 2 diabetes can control their blood sugar level with diet or diet and exercise alone. Chlorpropamide belongs to the class of drugs known as sulfonylureas. It works by stimulating the release of your body's natural insulin , thereby lowering your blood sugar. Chlorpropamide increases the amount of insulin released from the pancreas and helps your body to use insulin more efficiently. Generic chlorpropamide tablets are available.

Diabinese Dosage:

  • Dosage levels are determined by each individual's needs.
  • There is no fixed dosage regimen for the management of diabetes mellitus with Diabinese or any other hypoglycemic agent.
  • Usually, an initial daily dose of 250 milligrams is recommended for stable, middle-aged, non-insulin-dependent diabetics.
  • After 5 to 7 days, your doctor may adjust this dosage in increments of 50 to 125 milligrams every 3 to 5 days to achieve the best benefit.
  • Maintenance doses above 750 milligrams are not recommended.

Uses of Diabinese:

  • Diabinese is an oral antidiabetic medication used to treat type 2 (non-insulin-dependent) diabetes.
  • Chlorpropamide increases the amount of insulin released from the pancreas and helps your body to use insulin more efficiently.
  • Chlorpropamide may also be used for purposes other than those listed in this medication guide.
  • It probably acts by stimulating insulin secretion in the presence of functioning pancreatic islet tissue.

Side Effects of Diabinese:

Some common side effects reported with this medicine include:

  • Anemia and other blood disorders.
  • Diarrhea.
  • Loss of appetite.
  • Stomach upset.
  • Nausea.
  • Yellowing of the skin and eyes.
  • Cold sweat.
  • Fast heartbeat.
  • Nervousness.
  • Inflammation of the rectum and colon.
  • Pale skin.
  • Shallow breathing.

Warnings and precautions before taking Diabinese:

  • Before taking chlorpropamide, tell your doctor if you have a serious infection, illness, or injury.
  • If you have a heart condition, you may want to discuss this with your doctor.
  • If you are taking Diabinese, you should check your blood and urine periodically for the presence of abnormal sugar levels.
  • Before taking chlorpropamide, tell your doctor if you have type 1 diabetes.
  • Remember that it is important that you closely follow the diet and exercise regimen established by your doctor.
  • Do not take double or extra doses.

Drug Interaction:

  • The hypoglycemic action of sulfonylurea may be potentiated by certain drugs including nonsteroidal anti-inflammatory agents and other drugs that are highly protein bound.
  • Barbiturates should be used cautiously in patients receiving an oral hypoglycemic agent, since their action may be prolonged.
  • When you take Diabinese with certain other drugs, the effects of either could be increased, decreased, or altered.
  • Intolerance to alcohol (disulfiram-like reaction: flushing, sensation of warmth, giddiness, nausea, and occasionally tachycardia) may occur in patients treated with a sulfonylurea.

Overdosage:

  • After taking Diabinese, If you feel that overdose is suspected, then contact with your doctor immediately.
  • Overdosage of sulfonylureas including Diabinese can produce hypoglycemia.
  • Symptoms of overdose may include shakiness, nervousness, rapid heartbeat, hunger, or sweating.
  • Eating sugar or a sugar-based product will often correct the condition.
  • In case of overdose, call your local poison control center at 1-800-222-1222.

 

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